Variation and Population Genetics

Christopher J. Paradise and A. Malcolm Campbell

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This book describes and analyzes genetic and environmental factors that cause variation in individuals and populations. Data will be used to evaluate the processes by which variation is generated in organisms and how variation affects natural selection. Genetic factors include mutation, independent assortment, crossing over, and recombination. Environmental factors include gradients and differences in abiotic conditions. Genotype frequencies can be used to determine allele frequencies and this information can be used to determine whether a population is evolving at a genetic locus. The Hardy-Weinberg equilibrium will be applied as a null model to make this determination. Non-Mendelian genetics can affect the evolution of viruses and reassortment in viruses will be used to illustrate another mechanism that generates variation in organisms and how this mechanism relates to rapid evolution of viruses and the need for annual flu vaccines.

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Christopher J. Paradise

Christopher J. Paradise is professor of biology and environmental studies at Davidson College. He teaches introductory biology, ecology, entomology, and topical seminars on ecotoxicology and renewable natural resources. He also occasionally leads a study abroad program in India.  His research evaluates anthropogenic factors that influence insect biodiversity at a variety of scales.  His current research interests include effects of land use patterns on pollinator communities in parks.

A. Malcolm Campbell

A. Malcolm Campbell teaches biology at Davidson College, NC. He received national and international education awards: Genetics Society of America (2013); American Association for the Advancement of Science (2012); and American Society for Cell Biology (2006). He was the founding co-editor in chief of CBE Life Sciences Education; founding director of Genome Consortium for Active Teaching (GCAT); and member of the American Society for Cell Biology governing council (2012–2014).